Voice of China at EBMT 2026 | Professor Erlie Jiang / Dr. Xiaoyu Zhang: Exploring the Role of Third-Generation TKIs in Transplantation for Blast-Phase CML

Voice of China at EBMT 2026 | Professor Erlie Jiang / Dr. Xiaoyu Zhang: Exploring the Role of Third-Generation TKIs in Transplantation for Blast-Phase CML

From March 22 to 25, 2026, the 52nd Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT) was held in Madrid, Spain. As one of the most influential academic events in the field, the meeting brought together thousands of experts worldwide to discuss the latest advances in transplantation and cellular therapy.
Professor Haixia Fu: Applications and Advances of TPO Receptor Agonists and ATRA in the Treatment of ITP

Professor Haixia Fu: Applications and Advances of TPO Receptor Agonists and ATRA in the Treatment of ITP

From March 27 to 28, 2026, the 9th Beijing Conference on Thrombosis and Hemostasis, hosted by the Hematologic Immunology Branch of the Chinese Society of Immunology, together with the 7th Beijing Summit Forum on Hematologic Malignancies and Immunology, was successfully held in Beijing. The meeting brought together leading international and domestic experts, clinicians, and industry leaders to explore cutting-edge developments in thrombosis and hemostasis, hematologic malignancies, and immunology, while advancing academic exchange and innovation in the field.
Professor Heyu Ni: Interactions Between Platelets and the Immune System and Their Significance in Immune-Mediated Thrombocytopenia

Professor Heyu Ni: Interactions Between Platelets and the Immune System and Their Significance in Immune-Mediated Thrombocytopenia

From March 27 to 28, 2026, the 9th Beijing Conference on Thrombosis and Hemostasis and the 7th Beijing Summit Forum on Hematologic Malignancies and Immunology was successfully held in Beijing. The event brought together leading scholars, clinicians, and industry experts from around the world to exchange insights on cutting-edge developments in thrombosis and hemostasis, hematologic malignancies, and immunology, while shaping the future direction of the field.
Expert Interview | Prof. Shilpa Gupta Decodes Urothelial Carcinoma In-Depth: China’s Strength, Global Collaboration and Future Breakthroughs in the ADC Era

Expert Interview | Prof. Shilpa Gupta Decodes Urothelial Carcinoma In-Depth: China’s Strength, Global Collaboration and Future Breakthroughs in the ADC Era

In recent years, the rapid advancement of antibody-drug conjugates (ADCs) has completely reshaped the treatment paradigm across the entire disease course of urothelial carcinoma. Meanwhile, Chinese investigators and domestically developed innovative agents have gained ever-increasing influence in the global oncology landscape. Recently, we had the exclusive opportunity to interview Prof. Shilpa Gupta, a world-leading expert in urothelial carcinoma, Leading Principal Investigator of multiple pivotal international multicenter clinical trials from Cleveland Clinic. We conducted an in-depth, professional exchange with Prof. Gupta on core topics including the global positioning of China's clinical research in urological oncology, optimized pathways for cross-border research collaboration, the paradigm shift in diagnosis and treatment driven by ADCs, and the future disruptive breakthrough directions in the field. The following is the edited content of this interview.
Overcoming Antigen Escape: CD19/CD84 “If-Better” Dual CAR-T Cells Demonstrate Superior Control in CD19-Low B-ALL

Overcoming Antigen Escape: CD19/CD84 “If-Better” Dual CAR-T Cells Demonstrate Superior Control in CD19-Low B-ALL

At the recent EBMT 2026 Annual Meeting, Prof. Ane Altuna Mongelos from Hospital Clínic de Barcelona and IDIBAPS delivered a presentation titled "CD19/CD84 IF-BETTER dual CAR T cells demonstrate superior control of CD19-low B-ALL than single CAR19." The report explored novel pathways to overcome antigen escape in B-cell acute lymphoblastic leukemia (B-ALL) through a dual-targeting strategy.
Overcoming Delayed Engraftment: UM171 Expansion Technology and ATG-free Regimens Reshape the CBT Landscape 

Overcoming Delayed Engraftment: UM171 Expansion Technology and ATG-free Regimens Reshape the CBT Landscape 

As the landscape of hematopoietic stem cell transplantation (HSCT) continues to evolve, umbilical cord blood transplantation (CBT) maintains a critical position in the treatment of hematologic malignancies due to its unique immunological advantages. However, delayed engraftment and high non-relapse mortality (NRM) were once significant bottlenecks limiting its clinical utility. At a recent academic symposium, Professor Annalisa Ruggeri—Chair of the Cell Therapy & Immunobiology Working Party (CTIWP) of the European Society for Blood and Marrow Transplantation (EBMT) and Scientific Chair of Eurocord—delivered a profound presentation on "Regenerative Cord Blood Transplantation." Professor Ruggeri provided an in-depth analysis of the latest advancements, ranging from the optimization of donor selection and conditioning regimens to breakthrough ex vivo expansion technologies such as UM171. Her insights highlighted how technical innovations are overcoming traditional limitations of CBT to deliver superior survival outcomes for high-risk patients.
Breaking the Bottleneck in Severe Aplastic Anemia: Insights from EBMT Registry Big Data, Long-term IST Follow-up, and Novel Biological Predictors

Breaking the Bottleneck in Severe Aplastic Anemia: Insights from EBMT Registry Big Data, Long-term IST Follow-up, and Novel Biological Predictors

Severe Aplastic Anemia (SAA), as a highly heterogeneous bone marrow failure (BMF) disorder, continues to present a clinical challenge regarding the optimal choice between immunosuppressive therapy (IST) and hematopoietic stem cell transplantation (HSCT). During the recent European Society for Blood and Marrow Transplantation (EBMT) meeting, Professor Antonio Risitano provided a comprehensive overview of the Severe Aplastic Anemia Working Party (SAAWP) core activities, landmark clinical trials, and biological discoveries. This review deconstructs the key highlights of his presentation to provide clinicians with a cutting-edge international reference for evidence-based medicine.
Safety Profiles in the Real World: An EBMT Registry Study on the Evolution of Non-Relapse Mortality in 6,928 CAR-T Recipients

Safety Profiles in the Real World: An EBMT Registry Study on the Evolution of Non-Relapse Mortality in 6,928 CAR-T Recipients

The advent of Chimeric Antigen Receptor T-cell (CAR-T) therapy has fundamentally transformed the treatment landscape for relapsed/refractory (R/R) hematologic malignancies. However, as clinical adoption expands and follow-up durations extend, the management of treatment-related toxicities—specifically Non-Relapse Mortality (NRM)—has emerged as a critical bottleneck for long-term patient survival. At the 2026 Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), Dr. Charlotte Graham from London, representing the EBMT Transplant Complications Working Party (TCWP), presented a large-scale real-world study based on the EBMT registry. This analysis of nearly 7,000 CAR-T recipients provides high-granularity insights into NRM risk profiles and clinical intervention strategies.